Table 1.

Clinical features of epilepsy of seven patients

	Patient 2	Patient 3	Patient 5	Patient 6	Patient 8	Patient 10	Patient11
Age (years)	13	15	12	18	14	1.75	1.6
Sex	Female	Male	Male	Male	Female	Male	Female
ILAE classification	Epilepsy from unknown type with seizures unknown onset	Epilepsy from unknown type with seizures unknown onset	Focal epilepsy with focal seizures with leftward eye deviation and impaired awareness	West syndrome with infantile spasms and Lennox–Gastaut syndrome	Generalized epilepsy/epilepsy with myoclonic absences	Focal epilepsy with focal motor seizures (clonic and myoclonic) with impaired awareness	Focal epilepsy with focal motor seizures (clonic and myoclonic) with impaired awareness
Age of onset	8 days	5 days	2 years	4 months	22 months	2 weeks	1 week
Description	Neonatal convulsions, at 3.5y bilateral tonic–clonic seizure	Neonatal seizures; seizure-free	Focal seizures	Refractory tonic seizures. History of infantile spasms, myoclonic seizures, absences and atonic seizures Seizures appear daily	Complex febrile seizures. Refractory focal seizures, absences with eyelid myoclonia and myoclonic absences, GTCS Seizures appear daily	Focal seizures, seizure-free with oxcarbazepine	Focal seizures, seizure-free with oxcarbazepine
EEG	Multifocal epileptic discharges	Normal	Right-sided epileptiform discharges	Abundant multifocal epileptiform activity; left>right slowing.	Generalized 3-Hz spike and wave, progressive during sleep	Multifocal, mainly central (−parietal) spikes	Focal central spikes
Anti-epileptic treatment	Lamotrigine (history: Valproic acid)	None	Valproic acid 500/500 mg, clonidine 0.1 mg	Ketogenic diet, clonazepam, rufinamide, clobazam, cannabidiol, valproic acid, VNS	Lamotrigine, VNS (history: valproic acid, clobazam, ethosuximide, topiramate levetiracetam)	Oxcarbazepine

VNS: vagal nerve stimulator; GTCS: generalized tonic–clonic seizures.