Fig. 3.

–Sorensen–Dice similarity indices were used to indicate interaction similarity. For each species, different panels indicate gene pairs from different age groups (defined based on K_s peaks, see Materials and Methods for details), with panels arranged from left to right in chronological order (from younger to older groups). Overall, WGD-derived gene pairs have a higher interaction similarity as compared to SSD-derived gene pairs, especially for older duplicates (Mann–Whitney U test; P < 0.05). Effect sizes were measured using point-biserial correlation coefficients.