Table 2.

Meta-analysis of the association between Val66Met and MDD.

Val66met	Dominant model (MM+VM:VV)		Recessive model (MM:VV+VM)		Heterozygous model (VM:VV)		Homozygous model (MM:VV)		Allele models (M:V)
	P value	OR (95%)	P value	OR (95%)	P value	OR (95%)	P value	OR (95%)	P value	OR (95%)
Overall	0.18	1.08 [0.97, 1.20]	0.46	1.05 [0.92, 1.21]	0.78	0.98 [0.87, 1.11]	0.91	1.01 [0.86, 1.19]	0.67	1.02 [0.94, 1.10]
Caucasian	0.0001	1.40 [1.18, 1.66]	0.03	1.70 [1.05, 2.78]	0.10	1.20 [0.97, 1.48]	0.02	1.77 [1.08, 2.88]	0.01	1.25 [1.05, 1.48]
Asian	0.16	0.91 [0.79, 1.04]	0.85	1.01 [0.88, 1.17]	0.14	0.89 [0.77, 1.04]	0.53	0.95 [0.79, 1.13]	0.46	0.97 [0.89, 1.06]
Age < 60	0.58	1.04 [0.90, 1.20]	0.80	1.02 [0.88, 1.19]	0.99	1.00 [0.87, 1.15]	0.92	1.01 [0.84, 1.21]	0.77	1.01 [0.93, 1.11]
Age ≥ 60	0.41	1.17 [0.80, 1.72]	0.21	1.24 [0.88, 1.75]	0.63	0.88 [0.51, 1.50]	0.96	1.01 [0.68, 1.51]	0.63	1.08 [0.79, 1.46]