FIGURE 2.
LocusZoom (RRID:SCR_009257) plots of MHC region-wide studies. (A) For all participants (n = 3,641), rs9265901 (overlapping gene: HLA-B) was associated with late-onset asthma; (B) For White participants, rs55888430, an intron variant of HLA-DOB, was significantly associated with late-onset asthma; (C) For Black participants, rs117953947, which overlaps with HCG17, was significantly associated with late-onset asthma. We adjusted all regression models for age, sex, and four ancestries. The red and gray dotted lines represent the significance and suggestive thresholds.