. 2023 Jun 21;14:1173676. doi: 10.3389/fgene.2023.1173676

TABLE 3.

Associations and minor allele frequencies (MAF) of the leads SNPs across all strata.

			Pooled		EUR		AFR
Lead SNPs	MAF	MAF	OR ^a	p-value	OR ^a	p-value	OR ^a	p-value
rs9265901	0.15 (G)	EUR: 21%	1.31	3.62 × 10⁻⁵	1.66	6.91 × 10⁻⁴	1.79	0.03
rs9265901	0.15 (G)	AFR: 15%	1.31	3.62 × 10⁻⁵	1.66	6.91 × 10⁻⁴	1.79	0.03
rs55888430	0.03 (A)	EUR: 4%	2.24	2.84 × 10⁻⁴	3.05	8.85 × 10⁻⁶	0.32	0.26
rs55888430	0.03 (A)	AFR: 5%	2.24	2.84 × 10⁻⁴	3.05	8.85 × 10⁻⁶	0.32	0.26
rs117953947	0.04 (A)	EUR: 2%	1.14	0.76	0.46	0.30	19.5	9.97 × 10⁻⁵
rs117953947	0.04 (A)	AFR: 1%	1.14	0.76	0.46	0.30	19.5	9.97 × 10⁻⁵

^{^a}

Odds ratios represent the association between lead SNPs (rs9265901, rs55888430, rs117953947) and late-onset asthma, adjusted for covariates and additional SNPs in forward stepwise regression analyses. We adjusted all regression models for age, sex, and four ancestries.