Table 2. Effective concentrations of cinnamaldehyde, citronellal, anacardic acid and geraniol for inhibiting 50% and 95% of larval development (EC50 and EC95), confidence intervals (95% CI) and resistance factors for Haemonchus contortus isolates KOK, ISE and ECH.
| H. contortus isolates | EC50 (μM) | 95% CI | RF50 | EC95 (μM) | 95% CI | RF95 | |
|---|---|---|---|---|---|---|---|
| KOK | 7,396 | (6,766 - 8,083) | 1.02 | 21,594 | (16,127 - 32,738) | 1.53 | |
| Cinnamaldehyde | ISE | 7,232 | (6,787 - 7,706) | 1.00 | 14,115 | (11,510 - 19,164) | 1.00 |
| ECH | 6,542 | (6,319 - 6,772) | 0.91 | 13,031 | (11,529 - 15,183) | 0.92 | |
| KOK | 28,422 | (25,363 - 31,850) | 0.98 | 99,284 | (69,237 - 167,158) | 1.86 | |
| Citronellal | ISE | 28,883 | (26,809 - 31,117) | 1.00 | 53,319 | (41,555 - 86,254) | 1.00 |
| ECH | 31,816 | (28,463 - 35,565) | 1.10 | 81,654 | (57,513 - 148,312) | 1.53 | |
| KOK | 6.11 | (5.588 - 6.710) | 1.15 | 24.01 | (21.85 - 26.38) | 0.59 | |
| Anacardic acid | ISE | 5.31 | (4.929 - 5.719) | 1.00 | 40.85 | (37.93 - 44.01) | 1.00 |
| ECH | 7.38 | (6.858 - 7.931) | 1.39 | 18.34 | (17.06 - 19.72) | 0.45 | |
| KOK | 13,119 | (11,210 - 14,096) | 1.39 | 42,670 | (39,741 - 45,880) | 1.52 | |
| Geraniol | ISE | 9,430 | (8,822 - 10,081) | 1.00 | 28,154 | (26,338 - 30,097) | 1.00 |
| ECH | 12,560 | (11,867 - 13,293) | 1.33 | 35,318 | (33,369 - 37,379) | 1.26 |
EC50: effective concentration for inhibiting 50% of larval development; EC95: effective concentration for inhibiting 95% of larval development; 95% CI: 95% confidence interval; RF50: resistance factor for EC50 (EC50 of isolate X/EC50 for the ISE isolate); RF95: resistance factor for EC95 (EC95 of isolate X/EC95 for the ISE isolate).