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. 2023 Jun 19;32(2):e006023. doi: 10.1590/S1984-29612023027

Table 2. Effective concentrations of cinnamaldehyde, citronellal, anacardic acid and geraniol for inhibiting 50% and 95% of larval development (EC50 and EC95), confidence intervals (95% CI) and resistance factors for Haemonchus contortus isolates KOK, ISE and ECH.

H. contortus isolates EC50 (μM) 95% CI RF50 EC95 (μM) 95% CI RF95
KOK 7,396 (6,766 - 8,083) 1.02 21,594 (16,127 - 32,738) 1.53
Cinnamaldehyde ISE 7,232 (6,787 - 7,706) 1.00 14,115 (11,510 - 19,164) 1.00
ECH 6,542 (6,319 - 6,772) 0.91 13,031 (11,529 - 15,183) 0.92
KOK 28,422 (25,363 - 31,850) 0.98 99,284 (69,237 - 167,158) 1.86
Citronellal ISE 28,883 (26,809 - 31,117) 1.00 53,319 (41,555 - 86,254) 1.00
ECH 31,816 (28,463 - 35,565) 1.10 81,654 (57,513 - 148,312) 1.53
KOK 6.11 (5.588 - 6.710) 1.15 24.01 (21.85 - 26.38) 0.59
Anacardic acid ISE 5.31 (4.929 - 5.719) 1.00 40.85 (37.93 - 44.01) 1.00
ECH 7.38 (6.858 - 7.931) 1.39 18.34 (17.06 - 19.72) 0.45
KOK 13,119 (11,210 - 14,096) 1.39 42,670 (39,741 - 45,880) 1.52
Geraniol ISE 9,430 (8,822 - 10,081) 1.00 28,154 (26,338 - 30,097) 1.00
ECH 12,560 (11,867 - 13,293) 1.33 35,318 (33,369 - 37,379) 1.26

EC50: effective concentration for inhibiting 50% of larval development; EC95: effective concentration for inhibiting 95% of larval development; 95% CI: 95% confidence interval; RF50: resistance factor for EC50 (EC50 of isolate X/EC50 for the ISE isolate); RF95: resistance factor for EC95 (EC95 of isolate X/EC95 for the ISE isolate).