Binding capacity and functional activity against SARS-CoV-2 WT-Spike antigen at the pre-vaccine and post- second vaccine timepoints for active treatment, prior treatment, and healthy cohorts including (A) binding capacity of FcgR2a, FcgR2b, FcgR3a, FcgR3b, (B) functional activity of ADCD, ADCP and ADNP, (C) The Nightingale rose plots show the average of the z-scored value for antibody functions (in purple) and binding to FcgR (blue) in the Active Treatment, Prior Treatment and Healthy groups. Each wedge corresponds to a SARS-CoV-2 antibody feature, and the length of the wedge represents the magnitude of the response.