Table 1.

Patient characteristics prior to initiating alpelisib (N = 92).

	N (%)
Age
75-94 years	9 (9.8)
55-74 years	22 (23.9)
Less than 55 years	61 (66.3)
Body mass index*
Obese	33 (35.9)
Overweight	29 (31.5)
Normal	23 (25.0)
Lean	7 (7.6)
Glycemic history
Diabetes	31 (33.7)
Pre-diabetes only	9 (9.8)
Normoglycemia	52 (56.5)
Diagnosis of hypertension
Present	49 (53.3)
Absent	43 (46.7)
Diagnosis of hyperlipidemia
Present	38 (41.3)
Absent	54 (58.7)
Self-reported ancestry
Asian	12 (13.0)
Hispanic/Latino	14 (15.2)
African/Black	8 (8.7)
Hawaiian/Pacific Islander	1 (1.1)
Other	2 (2.2)
Non-Hispanic White	46 (50.0)
Unknown/decline to state	9 (9.8)

^*As described in the Methods, Results, and Supplementary Table S1, for n = 64 subjects it was necessary to estimate the pre-alpelisib value of BMI from a post-alpelisib value in their medical chart. Lean was defined as BMI < 20, normal was defined as BMI 20 to <25 (BMI 20 to <23 for Asians), overweight was defined as BMI 25 to <30 (BMI 23 to <27.5 for Asians), and obese was defined as BMI ≥30 (BMI ≥27.5 for Asians).^5,6