Table 1.
Patient characteristics prior to initiating alpelisib (N = 92).
N (%) | |
---|---|
Age | |
75-94 years | 9 (9.8) |
55-74 years | 22 (23.9) |
Less than 55 years | 61 (66.3) |
Body mass index* | |
Obese | 33 (35.9) |
Overweight | 29 (31.5) |
Normal | 23 (25.0) |
Lean | 7 (7.6) |
Glycemic history | |
Diabetes | 31 (33.7) |
Pre-diabetes only | 9 (9.8) |
Normoglycemia | 52 (56.5) |
Diagnosis of hypertension | |
Present | 49 (53.3) |
Absent | 43 (46.7) |
Diagnosis of hyperlipidemia | |
Present | 38 (41.3) |
Absent | 54 (58.7) |
Self-reported ancestry | |
Asian | 12 (13.0) |
Hispanic/Latino | 14 (15.2) |
African/Black | 8 (8.7) |
Hawaiian/Pacific Islander | 1 (1.1) |
Other | 2 (2.2) |
Non-Hispanic White | 46 (50.0) |
Unknown/decline to state | 9 (9.8) |
*As described in the Methods, Results, and Supplementary Table S1, for n = 64 subjects it was necessary to estimate the pre-alpelisib value of BMI from a post-alpelisib value in their medical chart. Lean was defined as BMI < 20, normal was defined as BMI 20 to <25 (BMI 20 to <23 for Asians), overweight was defined as BMI 25 to <30 (BMI 23 to <27.5 for Asians), and obese was defined as BMI ≥30 (BMI ≥27.5 for Asians).5,6