Table 1.
Basal, endocrine, and metabolic characteristics of all PCOS and all BMI-matched control participants.
| Variables | PCOS (n = 57) | Control (n = 57) | P value Unadjusted for age, BMI, and race | P value Adjusted for age, BMI, and race |
|---|---|---|---|---|
| Age (y) | 25.2 ± 1.0 | 31.3 ± 0.9 | <.001a | NA |
| BMI (kg/m2) | 35.2 ± 1.0 | 32.5 ± 1.2 | .089 | NA |
| WHR | 0.86 ± 0.01 | 0.80 ± 0.01 | <.001a | .007a |
| Ethnicity (n, %) | ||||
| AA | 11 (19.3) | 25 (43.9) | .009a | NA |
| Non-Hispanic White | 46 (80.7) | 32 (56.1) | .009a | NA |
| Hirsutism (mF-G) score | 11.23 ± 0.66 | 0.02 ± 02 | <.001a | <.001a |
| Hormonal analysis | ||||
| Total T (ng/dL) | 86.2 ± 5.4 | 37.8 ±6.6 | <.001a | .007a |
| Free T (ng/dL) | 0.96 ± 0.07 | 0.32 ±0.05 | <.001a | .001a |
| DHEAS (ng/mL) | 2,746.9 ± 194.8 | 6,668 ± 126.2 | <.001a | .003a |
| SHBG (nmol/L) | 174 ± 11 | 220 ±27 | .079 | .333 |
| Metabolic analysis | ||||
| Fasting glucose (mg/dL) | 83.9 ±2.1 | 84.0 ± 1.5 | .972 | .404 |
| INSo (μlU/mL) | 34.7 (5.4–190) | 9.6 (4.3–28.5) | <.001a | .001a |
| kITT (%/min) | 2.54 ±0.21 | 5.44 ±0.31 | <.001a | .001a |
| Prevalence or IR (n, %) | 45 (79) | 10(17.5) | <.001a | NA |
Note:Variables are expressed as mean ± standard error of the mean or as number or percentage (and range). For this analysis P<.05 is considered significant. AA = African American; BMI = body mass index; DHEAS = dehydroepiandrosterone sulfate; INS0 = fasting insulin levels; IR = insulin resistance; kITT = rate constant for plasma glucose disappearance during insulin tolerance test; mF-G = modified Ferriman-Gallwey; NA = not applicable; PCOS = polycystic ovary syndrome; SHBG = sex hormone-binding globulin; T = testosterone; WHR = waist-to-hip ratio.
P values considered statistically significant.
Ezeh. Menstrual cyclicity and dynamic state IR. Fertil Steril 2020.