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editorial
. 2023 Jun 12;52(5):1937–1952. doi: 10.1007/s10508-023-02623-5

Table 1.

Some studies sampling regret and detransition times

Study Quantity measured
Time until regret/detransition
#(N)
Regret or detransitioned
Definition of regret or detransition/
how measured
Intervention/criteria for intervention Age (sex) when treated
Total # people treated
Dhejne et al. (2014)

Median to regret

8 (all)

7.5 (FTMa)

8.5 (MTFb)

15:

5 FTM

10 MTF

Median age applied

22 FTM

35 MTF

Apply for new legal sex/record search Surgery/2 year evaluation, sterilization before starting

Median ages when all treated applied:

27 (FTM)

32 (MTF)

Total treated:

252 FTM

429 MTF

Wiepjes et al. (2018)

Median to regret

73.5 months after gonadectomy,

96.5 months after starting hormones (from Wiepjes et al. 2018, Table 4)

Average to regret

130 months after starting hormones

14:

3 FTM

11 MTF

Median age started hormones

31 FTM

38 MTF

Reverse hormones and expressing regret in visit/

record search

Gonadectomy/screening and a diagnostic phase

Median age first visit (for adults presenting):

25 (FTM)

33 (MTF)

Total with surgery:

885 FTM

1742 MTF with hormones for at least 1.5 years

Littman (2021)

Average to detransition

3.2 years FTM (2.7 SD)

5.4 years MTF (6.1 SD)

100:

69 FTM

31 MTF

Discontinued medication, had reversal surgery, or both/online survey Medication and/or surgery/criteria to start unspecified

Ave age sought medical care:

20 FTM (SD 4.2)

26 MTF (SD 7.5)

Total treated unknown

Vandenbussche (2022)

Average to detransition (includes time socially transitioned)

4.55 years FTM

6.37 years MTF

SD 3.55

237:

217 FTM

20 MTF

Identify as detransitioner/online survey Social (31%) or social + medical (65%)/criteria to start unspecified

Social (medical) transition ave age:

17.42 (20.09) FTM

23.63 (26.19) MTF

SD = 5.03 (5.36)

25% started medical transition under 18

Total treated unknown

aFTM: female-to-male

bMTF: male-to-female