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. 2023 Jul 5;14(7):399. doi: 10.1038/s41419-023-05906-w

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — Mouse islets were exposed to BMP-2 (50 ng/ml) or left non-exposed for 10 days. Relative mRNA expression of A Ins1, Ins2, Ucn3, MafA, Pdx1, Glp1r, and Hes-1, N = 5–12, B Ki67 and Cdk1, N = 5, and C Hey-1, N = 9 was analyzed using real-time PCR. Expression levels are normalized to control Ppia and Ctr data were set to 1 represented by the dotted horizontal line. Data were shown as means ± SD, *p < 0.05; **p < 0.01, ***p < 0.001 2-sided paired t-test vs. ctr on log10 transformed data.