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. 2023 Jul 5;14(7):399. doi: 10.1038/s41419-023-05906-w

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — Graph showing the correlation between RNA fold-change and A H3K27ac Ctr enriched peaks. B H3K4me3 Ctr enriched peaks. C H3K27ac BMP-2 enriched peaks. D H3K4me3 BMP-2 enriched peaks. X-axis: Log2 (FC RNA) Y-axis: Log2 (FC histone modification). *p < 0.05, ***p < 0.001 Spearman correlation test. E Biological process GO analysis on H3K27ac downregulated peaks associated with TSS of genes. F Biological process GO on H3K27ac BMP-2 upregulated peaks associated with TSS of genes. X-axis: Percent of genes in the GO with a differential peak associated with TSS. Circle: Number of genes in the GO with a BMP-2 regulated differential peak associated with their TSS.