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. 2023 Jul 5;14(7):399. doi: 10.1038/s41419-023-05906-w

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Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 7 — A Table depicting the top three enriched motifs in H3K27ac Control enriched (downregulated by BMP-2) peaks. B ChIP analysis showing the number of NeuroD1 binding sites (peaks) upregulated and downregulated by BMP-2. C Distribution of NeuroD1 occupied binding sites in the genome and differential NeuroD1 binding sites in response to BMP-2. D Biological processes GO analysis on BMP-2 downregulated NeuroD1 binding sites. X-axis: Percent of all genes in GO, that are near a differentially enriched binding site. Circle: Number of genes in the GO close to a differentially enriched binding site.