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. 2023 Apr 3;114(7):2939–2950. doi: 10.1111/cas.15793

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© 2023 The Authors. Cancer Science published by John Wiley & Sons Australia, Ltd on behalf of Japanese Cancer Association.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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MicroRNA (miR)‐29b‐containing small extracellular vesicles (sEV) suppresses phenotypic changes of human omentum tissue‐derived mesothelial cells (HPMCs) stimulated with transforming growth factor‐β1 (TGF‐β1). HPMCs were cultured with 10 ng/mL TGF‐β1 for 48 h. In some wells, HPMCs were transfected with miR‐29b in sEV (Exo‐miR‐29b) or negative control miR (Exo‐Control) and cultured with TGF‐β1. HPMCs were immunostained with mAbs to E‐cadherin, calretinin, and vimentin and their expressions were observed with fluorescein microscopy. No trtmt, without stimulation with TGF‐β1. Magnification, 400×.