TABLE 1.
Characteristics of the cohort studies included in the present pooled analysis
| Study | Initial population | Age range at baseline (years) | Follow‐up (start) | Follow‐up (end) | Average follow‐up period (years) | Number of subjects | Number of cases | Remarks | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Male | Female | EC (M, F) | GC (M, F) | ESCC | EA | GCC | GNCC | |||||||
| JPHC‐I | Japanese residents of five public health center areas in Japan | 40–59 | 1990 | 2013 | 20.9 | 20,383 | 22,201 | 221, 22 | 991, 394 | 201 | 13 | 76 | 1105 | Subjects of one public health center area were excluded due to lack of incidence data |
| JPHC‐II | Japanese residents of six public health center areas in Japan | 40–69 | 1993 | 2013 | 17.2 | 29,150 | 32,673 | 276, 29 | 1235, 498 | 243 | 8 | 101 | 1121 | |
| JACC | Residents from 45 areas throughout Japan | 40–79 | 1988 | 2009 | 13.2 | 24,755 | 35,659 | 149, 21 | 1091, 614 | 73 | 14 | 79 | 633 | 22 selected areas with cancer incidence follow‐up data were used in this analysis |
| MIYAGI‐I | Residents of 14 municipalities in Miyagi Prefecture, Japan | 40–64 | 1990 | 2014 | 21.3 | 21,094 | 22,657 | 259, 31 | 1432, 567 | 213 | 32 | 191 | 1331 | |
| MIYAGI‐II | Residents of three municipalities in Miyagi Prefecture, Japan | 40+ | 1984 | 1992 | 7.6 | 13,027 | 15,956 | 60, 8 | 332, 140 | 0 | 0 | 67 | 107 | |
| AICHI | Residents of two municipalities in Aichi Prefecture, Japan | 40–103 | 1985 | 2000 | 11.6 | 15,217 | 16,863 | 60, 7 | 405, 187 | 29 | 1 | 27 | 24 | |
| TAKAYAMA | Residents of Takayama city, Gifu Prefecture, Japan | 35–101 | 1992 | 2008 | 13.6 | 13,398 | 15,568 | 57, 10 | 411, 218 | 49 | 3 | 10 | 81 | |
| OHSAKI | Residents of 14 municipalities in Miyagi Prefecture, Japan | 40–79 | 1994 | 2008 | 10.7 | 21,498 | 23,196 | 175, 38 | 954, 375 | 160 | 13 | 131 | 746 | |
| OSAKA | Residents of four municipalities in Osaka Prefecture, Japan | 40–97 | 1983 | 1998–2000 | 11.4 | 15,920 | 17,973 | 80, 10 | 537, 265 | 24 | 2 | 21 | 158 | |
| LSS | Atomic bomb survivors in Hiroshima and Nagasaki, Japan | 46–104 | 1991 | 2003 | 10.8 | 6541 | 10,518 | 45, 11 | 263, 186 | 46 | 0 | 25 | 314 |
LSS originally started in 1950 This analysis included subjects who responded to the 1991 survey |
| Total | 180,983 | 213,264 | 1382, 187 | 7651, 3444 | 1038 | 86 | 728 | 5620 | ||||||
Abbreviations: AICHI, The Three‐Prefecture Cohort Study in Aichi; EA, esophageal adenocarcinoma; EC, esophageal cancer; ESCC, esophageal squamous cell carcinoma; F, female; GC, gastric cancer; GCC, gastric cardia cancer; GNCC, gastric noncardia cancer; JACC, The Japan Collaborative Cohort Study; JPHC, The Japan Public Health Center‐based Prospective Study; LSS, Life Span Study; M, male; MIYAGI‐I, The Miyagi Cohort Study; MIYAGI‐II, The Three‐Prefecture Cohort Study in Miyagi; OHSAKI, The Ohsaki Cohort Study; Osaka, The Three‐Prefecture Cohort Study in Osaka; TAKAYAMA, The Takayama Study. In ESCC and EA, we excluded MIYAGI‐II, in which no information on histological type was available.