TABLE 7.

Comparison between total and ICU length of stay among the different genotypes in severe COVID-19 patients.

SNP	Genotypes			Significance p-value
ACE-1 (rs4343)	Homozygous GG	Heterozygous AG	Homozygous AA
Total length of stay in days (Mean ± SD)	28.33 ± 7.57	13.57 ± 5.53	15.10 ± 6.71	0.001*
ICU length of stay in days (Mean ± SD)	17.67 ± 5.86	12.00 ± 4.89	12.59 ± 5.18	0.196

TMPRSS2 (rs12329760)	Homozygous GG	Heterozygous GC	Homozygous CC
Total length of stay in days (Mean ± SD)	17.14 ± 4.67	14.97 ± 7.23	13.40 ± 5.89	0.358
ICU length of stay in days (Mean ± SD)	14.14 ± 4.85	12.41 ± 5.07	12.10 ± 6.06	0.694

ACE-2 (rs908004)	Homozygous GG	Heterozygous GT	Homozygous TT
Total length of stay in days (Mean ± SD)	13.74 ± 6.10	14.44 ± 5.58	23.60 ± 9.13	0.008*
ICU length of stay in days (Mean ± SD)	11.84 ± 5.17	12.92 ± 5.02	13.80 ± 6.76	0.690

ACE, angiotensin converting enzyme; TMPRSS2, type 2 transmembrane serine protease; ICU, intensive care unit; SD, standard deviation. *Significance level at p-value <0.05.