Table 5.

Diagnostic performance of the QF-Ag or the QF-Mg at M1 using manufacturer’s cut-offs for prediction of CMV reactivation in the R+ KTR cohort.

Cut-off (IU/ml)	Time point	Follow-up	Sensitivity* % [95% CI]	Specificity* % [95% CI]	PPV* % [95% CI]	NPV* % [95% CI]
QF-Ag < 0.2	M1	M1–M4	25.0 [3.2; 65.1]	78.0 [64.0; 88.5]	15.4 [1.9; 45.4]	86.7 [73.2; 95.0]
	M1	M1–M6	27.3 [6.0; 61]	78.7 [64.3; 89.3]	23.1 [5.0; 53.8]	82.2 [68.0; 92.0]
	M1	M1–M12	28.6 [8.4; 58.1]	79.5 [64.7; 90.2]	30.8 [9.1; 61.4]	77.8 [62.9; 88.8]
QF-Mg < 0.5	M1	M1–M4	37.5 [8.5; 75.5]	80.0 [66.3; 90.0]	23.1 [5.0; 53.8]	88.9 [76.0; 96.3]
	M1	M1–M6	45.5 [16.8; 76.6]	83.0 [69.2; 92.4]	38.5 [13.9; 68.4]	86.7 [73.2; 95.0]
	M1	M1–M12	42.9 [17.7; 71.1]	84.1 [69.9; 93.4]	46.1 [19.2; 74.9]	82.2 [67.9; 92.0]

PPV, positive predictive value; NPV, negative predictive value; and CI, confidence interval.

^*Calculated in patients with data available over the study period.