Anti‐inflammatory response of macrophages induced by CCM‐CoFe PBA, CoFe PBA, and CCM in vitro. a–c) The effects of CCM‐CoFe PBA, CCM and CoFe PBA treatment on the expression of IL‐1β, IL‐6 and TNF‐α were quantitatively detected by ELISA. d–k) Flow cytometry was used to investigate the effect of CCM‐CoFe PBA and CCM on the polarization of mouse macrophage RAW264.7 into M2 type after LPS+IFN‐γ activation into M1 phenotype. The results are expressed as means ± SD (standard deviation) of triplicate experiments. A one‐way ANOVA test of multiple comparisons followed by Dunnett's post‐hoc test was used in all analyses. * p < 0.05, **
p < 0.01, ***
p < 0.001, ****
p < 0.0001, ns, not significant.