Figure 8.

Biocompatibility of SENDs. A) In vitro cytotoxicity of SENDs toward INS‐1 cells after incubation for 24 h. B–F) Serum levels of B) liver function indicators, C) kidney function indicators, and D–F) blood parameters in normal mice (control group) and mice administered intravenously with SENDs, 24 h after injection. G) H&E staining, Masson staining and Congo red staining of major organs (heart, liver, spleen, pancreas, kidney) of normal mice after injection with SENDs (10 mg kg⁻¹) for 30 days. Scale bar: 100 µm. Data represent means ± S.D. from six independent replicates.