Table 1.
All subjects (n=338) |
Healthy subjects (n=208) |
Patients living with T2D and/or obesity (n=130) |
p value | |
---|---|---|---|---|
Sex ratio: women: (n, %) | 200 (56.9) | 112 (50.9) | 88 (67.2) | 0.003 |
Age (years) | 24 [21;49] | 21 [20;24] | 52 [42;60] | <0.0001 |
BMI (kg/m²) | 23.9 [21;33.2] | 21.6 [19.7;23.5] | 37.1 [32.4;43.3] | <0.0001 |
WC (cm): - women - men |
78.8 [68.5;114] 83.5 [76;103] |
69 [64.6;73.9] 79 [75;85.5] |
115.5 [105.3;127] 115 [107;131] |
<0.0001 <0.0001 |
Type 2 diabetes (n, %) | 102 (29.1) | 0 | 102 (77.9) | <0.0001 |
Obesity (n, %) | 112 (31.9) | 0 | 72 (54.9) | <0.0001 |
Dyslipidemia (n, %) | 72 (20) | 0 | 72 (54.9) | <0.0001 |
Arterial hypertension (n, %) | 70 (20) | 0 | 70 (53.3) | <0.0001 |
Lipid profile | ||||
Total cholesterol (mmol/L) | 4.4 ( ± 0.9) | 4.4 ( ± 0.8) | 4.3 ( ± 0.3) | 0.07 |
Triglycerides (mmol/L) | 0.9 [0.4;1.3] | 0.8 [0.6;1.1] | 1.4 [1.0;2.1] | <0.0001 |
HDL (mmol/L) | 1.3 [1;1.5] | 1.4 [1.2;1.7] | 1.1 [0.9;1.3] | <0.0001 |
LDL (mmol/L) | 2.5 ( ± 0.8) | 2.5 [2.0;1.7] | 2.6 [1.8;3.1] | 0.16 |
Glucose profile | ||||
Fasting plasma glucose (mmol/L) | 4.9 [4.6;6.3] | 4.7 [4.4;4.9] | 7.3 [5.5;9.4] | <0.0001 |
Fasting plasma insulinemia (mUI/L) | 8.2 [5.9;12.9] | 7.1 [5.2;9.2] | 17.3 [12.4;24.9] | <0.0001 |
HOMA-IR | 1.7 [1.2;2.9] | 1.5 [1.0;1.9] | 4.8 [2.9;8.1] | <0.0001 |
Data expressed as mean ± standard deviation (SD) or as median [25th percentile;75th percentile].
BMI, body mass index; HOMA-IR, homeostatic model assessment of insulin resistance; HDL, high-density lipoprotein; LDL, low-density lipoprotein; T2D, type 2 diabetes; WC, waist circumference.