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. 2023 Feb 27;17(7):1324–1342. doi: 10.1002/1878-0261.13396

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© 2023 The Authors. Molecular Oncology published by John Wiley & Sons Ltd on behalf of Federation of European Biochemical Societies.

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Fig. 1 — Immunohistochemical analysis of furin expression in papillary thyroid cancer (PTC) TMA. Representative examples of tumors showing (A) low expression and (B) high expression of furin. (20×/0.70 objectives on an Olympus BX 51 microscope (Olympus America Inc, Center Valley, PA, USA) with the inset showing a 40× 0.85 aperture magnified view of the same TMA spot; scale bar in A and B = 200 μm). (C) Kaplan–Meier survival analysis for the prognostic significance of furin expression in PTC. PTC patients with overexpression of furin had reduced disease‐free survival at 5 years compared to tumors showing low expression of Furin (P = 0.0003).