Table 1.
Cancer type | Overall | Men | Rate ratio (95% CI)a | Women | Rate ratio (95% CI)b | 20-49 years | 50-69 years | ≥70 years |
---|---|---|---|---|---|---|---|---|
American Indian/Alaska Native individuals | ||||||||
All cancers | 214.9 | 249.2 | 0.99 (0.96 to 1.03) | 189.9 | 1.04 (1.00 to 1.08)c | 28.7 | 279.6 | 968.6 |
Oral cavity and pharynx | 2.9 | 4.3 | 0.75 (0.57 to 0.97)c | 1.7 | 0.79 (0.53 to 1.15) | — | 5.6 | 8.4 |
Esophagus | 5.1 | 8.1 | 0.77 (0.62 to 0.93)c | 2.6 | 1.26 (0.92 to 1.69) | — | 8.1 | 20.9 |
Stomach | 7.8 | 10.7 | 2.68 (2.23 to 3.19)c | 5.6 | 2.78 (2.23 to 3.42)c | 2.1 | 9.8 | 30.8 |
Colorectum | 23.5 | 27.9 | 1.30 (1.17 to 1.45)c | 19.8 | 1.30 (1.16 to 1.46)c | 4.9 | 30.7 | 97.0 |
Liver | 17.6 | 24.8 | 2.10 (1.88 to 2.34)c | 12.0 | 2.33 (2.02 to 2.68)c | 1.0 | 32.2 | 67.3 |
Pancreas | 14.4 | 16.1 | 0.88 (0.76 to 1.01) | 12.9 | 0.95 (0.83 to 1.09) | 1.4 | 20.4 | 63.7 |
Lung | 45.2 | 50.1 | 0.84 (0.77 to 0.91)c | 41.5 | 0.94 (0.87 to 1.01) | 1.9 | 57.9 | 225.6 |
Soft tissue including heart | 1.4 | 1.6 | 0.77 (0.47 to 1.19) | 1.3 | 0.87 (0.53 to 1.34) | 0.6 | 1.8 | 4.8 |
Breast | 24.8 | — | — | 24.8 | 0.91 (0.82 to 1.00) | 6.9 | 31.3 | 97.1 |
Cervix | 4.1 | — | — | 4.1 | 1.43 (1.10 to 1.82)c | 2.8 | 7.3 | — |
Uterus | 6.5 | — | — | 6.5 | 1.00 (0.82 to 1.21) | 1.3 | 9.7 | 25.2 |
Ovary | 8.3 | — | — | 8.3 | 0.92 (0.77 to 1.09) | 2.1 | 10.6 | 33.2 |
Prostate | 25.4 | 25.4 | 1.02 (0.90 to 1.16) | — | — | — | 14.8 | 164.3 |
Bladder | 3.3 | 4.7 | 0.43 (0.32 to 0.57)c | 2.2 | 0.74 (0.51 to 1.03) | — | 2.9 | 18.9 |
Kidney | 9.2 | 13.2 | 1.79 (1.52 to 2.08)c | 5.9 | 1.92 (1.55 to 2.35)c | 1.1 | 12.7 | 40.3 |
CNS | 3.5 | 3.8 | 0.45 (0.33 to 0.59)c | 3.2 | 0.59 (0.44 to 0.77)c | 1.4 | 5.0 | 10.2 |
Non-Hodgkin lymphoma | 6.4 | 8.6 | 0.88 (0.71 to 1.07) | 4.8 | 0.85 (0.67 to 1.07) | 0.7 | 7.3 | 31.8 |
Myeloma | 4.3 | 5.2 | 1.02 (0.78 to 1.30) | 3.6 | 1.18 (0.89 to 1.53) | — | 4.8 | 21.9 |
Leukemia | 6.3 | 8.1 | 0.70 (0.57 to 0.84)c | 4.8 | 0.76 (0.60 to 0.95)c | 1.5 | 5.7 | 30.4 |
Asian individuals | ||||||||
All cancers | 126.8 | 147.9 | 0.59 (0.58 to 0.60)c | 111.4 | 0.61 (0.60 to 0.62)c | 15.9 | 146.7 | 613.0 |
Oral cavity and pharynx | 2.8 | 4.3 | 0.74 (0.69 to 0.80)c | 1.6 | 0.75 (0.68 to 0.84)c | 0.6 | 4.3 | 10.3 |
Esophagus | 2.1 | 3.5 | 0.33 (0.31 to 0.36)c | 1.0 | 0.45 (0.39 to 0.52)c | 0.2 | 2.8 | 9.4 |
Stomach | 6.0 | 7.6 | 1.90 (1.79 to 2.01)c | 4.8 | 2.36 (2.21 to 2.51)c | 1.0 | 6.6 | 28.7 |
Colorectum | 12.5 | 15.0 | 0.70 (0.67 to 0.73)c | 10.5 | 0.69 (0.66 to 0.72)c | 2.1 | 15.3 | 55.9 |
Liver | 11.4 | 17.0 | 1.43 (1.38 to 1.49)c | 7.0 | 1.36 (1.29 to 1.44)c | 1.1 | 14.7 | 53.6 |
Pancreas | 10.5 | 11.4 | 0.62 (0.59 to 0.65)c | 9.7 | 0.71 (0.68 to 0.75)c | 0.7 | 11.0 | 55.6 |
Lung | 26.1 | 33.5 | 0.56 (0.55 to 0.58)c | 20.6 | 0.47 (0.45 to 0.48)c | 1.6 | 27.9 | 139.0 |
Soft tissue including heart | 1.2 | 1.4 | 0.66 (0.58 to 0.74)c | 1.1 | 0.73 (0.64 to 0.83)c | 0.5 | 1.5 | 4.2 |
Breast | 15.9 | — | — | 15.9 | 0.58 (0.56 to 0.60)c | 4.5 | 25.1 | 51.5 |
Cervix | 2.1 | — | — | 2.1 | 0.73 (0.67 to 0.80)c | 0.8 | 3.5 | 5.3 |
Uterus | 4.6 | — | — | 4.6 | 0.70 (0.66 to 0.75)c | 0.7 | 7.7 | 17.1 |
Ovary | 6.0 | — | — | 6.0 | 0.66 (0.63 to 0.70)c | 1.2 | 10.7 | 19.0 |
Prostate | 11.6 | 11.6 | 0.47 (0.44 to 0.49)c | — | — | — | 5.3 | 78.5 |
Bladder | 2.3 | 3.9 | 0.36 (0.33 to 0.38)c | 1.2 | 0.39 (0.34 to 0.44)c | 0.1 | 1.3 | 15.0 |
Kidney | 2.1 | 3.1 | 0.42 (0.39 to 0.46)c | 1.3 | 0.44 (0.39 to 0.49)c | 0.2 | 2.4 | 10.7 |
CNS | 3.0 | 3.9 | 0.46 (0.43 to 0.50)c | 2.3 | 0.43 (0.39 to 0.47)c | 1.0 | 4.4 | 10.3 |
Non-Hodgkin lymphoma | 4.9 | 6.4 | 0.66 (0.62 to 0.70)c | 3.7 | 0.67 (0.63 to 0.72)c | 0.4 | 4.7 | 26.7 |
Myeloma | 2.0 | 2.6 | 0.49 (0.45 to 0.54)c | 1.6 | 0.54 (0.48 to 0.60)c | 0.1 | 1.9 | 11.7 |
Leukemia | 4.4 | 5.9 | 0.50 (0.47 to 0.54)c | 3.3 | 0.52 (0.48 to 0.55)c | 0.7 | 4.1 | 22.3 |
Black individuals | ||||||||
All cancers | 241.5 | 298.2 | 1.19 (1.18 to 1.20)c | 206.5 | 1.13 (1.12 to 1.14)c | 30.2 | 327.8 | 1070.8 |
Oral cavity and pharynx | 3.5 | 6.0 | 1.04 (1.00 to 1.09) | 1.7 | 0.80 (0.74 to 0.86)c | 0.5 | 6.4 | 11.7 |
Esophagus | 4.0 | 6.5 | 0.61 (0.59 to 0.64)c | 2.1 | 1.02 (0.96 to 1.09) | 0.4 | 7.2 | 14.5 |
Stomach | 6.9 | 9.8 | 2.46 (2.36 to 2.56)c | 4.9 | 2.40 (2.28 to 2.51)c | 1.0 | 8.3 | 31.8 |
Colorectum | 24.1 | 30.8 | 1.44 (1.41 to 1.47)c | 19.4 | 1.28 (1.25 to 1.31)c | 4.1 | 33.3 | 100.5 |
Liver | 11.4 | 17.9 | 1.51 (1.47 to 1.55)c | 6.6 | 1.28 (1.23 to 1.33)c | 1.0 | 21.9 | 39.7 |
Pancreas | 19.3 | 21.8 | 1.19 (1.16 to 1.22)c | 17.4 | 1.28 (1.25 to 1.31)c | 1.5 | 27.3 | 87.7 |
Lung | 50.2 | 68.7 | 1.15 (1.13 to 1.17)c | 37.6 | 0.85 (0.84 to 0.86)c | 2.5 | 70.5 | 235.7 |
Soft tissue including heart | 2.1 | 2.1 | 1.02 (0.94 to 1.11) | 2.0 | 1.37 (1.28 to 1.47)c | 0.9 | 2.9 | 6.1 |
Breast | 38.7 | — | — | 38.7 | 1.41 (1.39 to 1.44)c | 12.1 | 58.7 | 125.3 |
Cervix | 4.7 | — | — | 4.7 | 1.64 (1.56 to 1.72)c | 2.4 | 7.0 | 10.8 |
Uterus | 13.1 | — | — | 13.1 | 2.00 (1.95 to 2.06)c | 1.1 | 21.7 | 52.4 |
Ovary | 8.0 | — | — | 8.0 | 0.88 (0.85 to 0.91)c | 1.1 | 12.9 | 30.5 |
Prostate | 52.6 | 52.6 | 2.12 (2.08 to 2.16)c | — | — | 0.5 | 38.2 | 328.6 |
Bladder | 4.7 | 7.3 | 0.66 (0.63 to 0.69)c | 3.1 | 1.02 (0.96 to 1.08) | 0.2 | 4.2 | 26.8 |
Kidney | 4.6 | 7.1 | 0.96 (0.92 to 1.00)c | 2.9 | 0.94 (0.89 to 0.99)c | 0.7 | 6.1 | 20.1 |
CNS | 3.8 | 4.7 | 0.55 (0.52 to 0.58)c | 3.1 | 0.57 (0.54 to 0.60)c | 1.2 | 5.6 | 12.4 |
Non-Hodgkin lymphoma | 5.3 | 7.0 | 0.72 (0.69 to 0.75)c | 4.1 | 0.74 (0.70 to 0.77)c | 1.1 | 6.4 | 23.4 |
Myeloma | 8.2 | 10.2 | 1.97 (1.89 to 2.05)c | 6.9 | 2.27 (2.18 to 2.36)c | 0.5 | 8.7 | 43.7 |
Leukemia | 7.1 | 9.3 | 0.80 (0.77 to 0.83)c | 5.7 | 0.89 (0.86 to 0.93)c | 1.5 | 7.6 | 33.1 |
Latino individuals | ||||||||
All cancers | 148.5 | 177.2 | 0.71 (0.70 to 0.71)c | 128.4 | 0.70 (0.70 to 0.71)c | 18.9 | 172.6 | 715.0 |
Oral cavity and pharynx | 2.0 | 3.2 | 0.56 (0.52 to 0.59)c | 1.1 | 0.52 (0.47 to 0.57)c | 0.3 | 2.8 | 9.1 |
Esophagus | 2.7 | 4.9 | 0.46 (0.44 to 0.48)c | 0.9 | 0.43 (0.39 to 0.48)c | 0.3 | 3.7 | 11.9 |
Stomach | 6.5 | 8.1 | 2.03 (1.95 to 2.12)c | 5.4 | 2.65 (2.53 to 2.77)c | 1.6 | 7.9 | 27.1 |
Colorectum | 14.8 | 18.7 | 0.87 (0.85 to 0.90)c | 11.7 | 0.77 (0.75 to 0.79)c | 2.4 | 18.5 | 66.5 |
Liver | 12.7 | 18.0 | 1.52 (1.48 to 1.56)c | 8.4 | 1.64 (1.58 to 1.70)c | 0.7 | 19.4 | 56.4 |
Pancreas | 12.4 | 13.6 | 0.74 (0.72 to 0.76)c | 11.3 | 0.84 (0.81 to 0.86)c | 0.8 | 15.0 | 62.2 |
Lung | 20.8 | 28.0 | 0.47 (0.46 to 0.48)c | 15.5 | 0.35 (0.34 to 0.36)c | 0.9 | 20.7 | 115.4 |
Soft tissue including heart | 1.5 | 1.6 | 0.77 (0.71 to 0.84)c | 1.4 | 0.92 (0.85 to 1.00)c | 0.6 | 2.0 | 4.4 |
Breast | 19.0 | — | — | 19.0 | 0.69 (0.68 to 0.71)c | 5.1 | 28.4 | 66.2 |
Cervix | 3.4 | — | — | 3.4 | 1.19 (1.12 to 1.25)c | 2.0 | 4.8 | 7.2 |
Uterus | 6.0 | — | — | 6.0 | 0.92 (0.88 to 0.96)c | 0.9 | 9.5 | 23.0 |
Ovary | 6.7 | — | — | 6.7 | 0.74 (0.71 to 0.76)c | 1.2 | 10.5 | 24.7 |
Prostate | 20.9 | 20.9 | 0.84 (0.82 to 0.87)c | — | — | 0.1 | 10.8 | 139.8 |
Bladder | 3.2 | 5.3 | 0.48 (0.46 to 0.51)c | 1.7 | 0.57 (0.53 to 0.61)c | 0.1 | 2.1 | 20.0 |
Kidney | 4.5 | 6.5 | 0.87 (0.84 to 0.91)c | 2.9 | 0.93 (0.87 to 0.98)c | 0.5 | 5.6 | 21.0 |
CNS | 4.1 | 4.8 | 0.57 (0.54 to 0.59)c | 3.6 | 0.66 (0.62 to 0.69)c | 1.1 | 5.7 | 15.4 |
Non-Hodgkin lymphoma | 6.1 | 7.8 | 0.81 (0.77 to 0.84)c | 4.8 | 0.86 (0.82 to 0.90)c | 0.6 | 5.7 | 33.0 |
Myeloma | 3.6 | 4.3 | 0.84 (0.79 to 0.89)c | 3.0 | 0.98 (0.92 to 1.04) | 0.2 | 3.7 | 19.4 |
Leukemia | 5.6 | 7.0 | 0.60 (0.58 to 0.63)c | 4.5 | 0.70 (0.67 to 0.74)c | 1.4 | 4.8 | 26.7 |
Native Hawaiian and Pacific Islander individuals | ||||||||
All cancers | 197.3 | 205.6 | 0.82 (0.77 to 0.87)c | 192.1 | 1.05 (0.99 to 1.11) | 43.7 | 288.4 | 743.1 |
Oral cavity and pharynx | 3.7 | 4.7 | 0.82 (0.55 to 1.18) | 2.8 | 1.32 (0.74 to 2.15) | 1.7 | 7.4 | — |
Esophagus | 2.8 | 4.5 | 0.42 (0.27 to 0.62)c | — | — | — | 4.9 | 9.6 |
Stomach | 8.7 | 11.2 | 2.81 (2.09 to 3.70)c | 6.7 | 3.32 (2.34 to 4.55)c | 2.3 | 10.4 | 35.8 |
Colorectum | 14.6 | 16.6 | 0.77 (0.62 to 0.95)c | 12.6 | 0.83 (0.65 to 1.04) | 5.4 | 24.4 | 38.7 |
Liver | 15.1 | 21.6 | 1.83 (1.51 to 2.20)c | 9.0 | 1.76 (1.30 to 2.32)c | 4.8 | 24.7 | 45.1 |
Pancreas | 12.2 | 11.8 | 0.64 (0.49 to 0.84)c | 12.5 | 0.92 (0.71 to 1.17) | 1.6 | 17.5 | 51.5 |
Lung | 38.5 | 47.5 | 0.80 (0.69 to 0.91)c | 30.7 | 0.69 (0.59 to 0.81)c | 3.2 | 53.5 | 175.8 |
Soft tissue including heart | 2.7 | 1.9 | 0.90 (0.46 to 1.61) | 3.3 | 2.23 (1.36 to 3.46)c | — | 5.4 | — |
Breast | 33.2 | — | — | 33.2 | 1.21 (1.05 to 1.39)c | 8.2 | 61.0 | 95.8 |
Cervix | 6.9 | — | — | 6.9 | 2.43 (1.75 to 3.30)c | 4.4 | 8.7 | 15.5 |
Uterus | 19.5 | — | — | 19.5 | 2.99 (2.47 to 3.58)c | 9.4 | 34.1 | 38.0 |
Ovary | 7.8 | — | — | 7.8 | 0.86 (0.63 to 1.16) | — | 13.3 | 22.0 |
Prostate | 23.0 | 23.0 | 0.92 (0.74 to 1.13) | — | — | — | 16.4 | 143.6 |
Bladder | 4.0 | 6.2 | 0.57 (0.36 to 0.84)c | 2.1 | 0.71 (0.36 to 1.26) | — | — | 24.0 |
Kidney | 3.7 | 5.5 | 0.74 (0.49 to 1.08) | 2.1 | 0.68 (0.35 to 1.18) | — | 5.9 | 13.9 |
CNS | 3.8 | 3.9 | 0.46 (0.27 to 0.72)c | 3.7 | 0.69 (0.43 to 1.04) | — | 5.3 | 12.5 |
Non-Hodgkin lymphoma | 6.8 | 7.2 | 0.74 (0.52 to 1.04) | 6.4 | 1.15 (0.79 to 1.61) | 1.5 | 7.9 | 29.8 |
Myeloma | 3.8 | 4.4 | 0.86 (0.52 to 1.32) | 3.4 | 1.12 (0.66 to 1.77) | — | 4.9 | 19.2 |
Leukemia | 7.9 | 9.5 | 0.81 (0.59 to 1.09) | 6.5 | 1.02 (0.71 to 1.42) | 2.3 | 8.8 | 32.4 |
White individuals | ||||||||
All cancers | 212.3 | 250.8 | — | 183.0 | — | 23.5 | 255.7 | 1020.3 |
Oral cavity and pharynx | 3.8 | 5.8 | — | 2.1 | — | 0.5 | 6.3 | 14.7 |
Esophagus | 6.0 | 10.6 | — | 2.1 | — | 0.6 | 9.4 | 25.0 |
Stomach | 2.9 | 4.0 | — | 2.0 | — | 0.5 | 3.6 | 12.9 |
Colorectum | 18.1 | 21.4 | — | 15.2 | — | 3.2 | 22.4 | 80.2 |
Liver | 8.2 | 11.8 | — | 5.1 | — | 0.6 | 13.2 | 34.3 |
Pancreas | 15.8 | 18.4 | — | 13.6 | — | 1.2 | 20.1 | 76.7 |
Lung | 51.1 | 59.7 | — | 44.3 | — | 2.4 | 66.6 | 251.3 |
Soft tissue including heart | 1.8 | 2.1 | — | 1.5 | — | 0.6 | 2.2 | 6.5 |
Breast | 27.4 | — | — | 27.4 | — | 6.5 | 37.2 | 106.7 |
Cervix | 2.9 | — | — | 2.9 | — | 1.9 | 4.2 | 4.6 |
Uterus | 6.5 | — | — | 6.5 | — | 0.7 | 9.4 | 28.4 |
Ovary | 9.0 | — | — | 9.0 | — | 1.4 | 12.9 | 37.4 |
Prostate | 24.8 | 24.8 | — | — | — | 0.2 | 12.8 | 165.8 |
Bladder | 6.4 | 10.9 | — | 3.0 | — | 0.2 | 4.6 | 39.2 |
Kidney | 5.1 | 7.4 | — | 3.1 | — | 0.5 | 6.3 | 24.2 |
CNS | 6.9 | 8.5 | — | 5.4 | — | 2.2 | 10.4 | 22.0 |
Non-Hodgkin lymphoma | 7.4 | 9.7 | — | 5.6 | — | 0.6 | 6.1 | 42.3 |
Myeloma | 4.0 | 5.2 | — | 3.1 | — | 0.2 | 3.6 | 22.8 |
Leukemia | 8.7 | 11.7 | — | 6.3 | — | 1.1 | 6.8 | 48.3 |
Rate ratios compare to White men. “—” signifies statistic not displayed because of fewer than 10 cases or not applicable. CI = confidence Interval; CNS = central nervous system.
Rate ratios compared to White women.
Denotes statistical significance (P < .05).