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. 2023 May 9;109(1):138–146. doi: 10.4269/ajtmh.22-0773

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Figure 3. — Comparison of Net OD 1.0 anti–PfCSP antibody levels in infants and children with levels in 18–35-year-old adults protected against Plasmodium falciparum parasitemia after CHMI. Horizontal arms represent medians and are bracketed by the interquartile range. Each point represents the results for a unique participant. Filled circles (⬤) represent participants not infected after CHMI; crossed circles (⊗) represent participants who did not undergo CHMI. Median antibody levels were significantly higher than the median for protected adults for children ages 6–11 months and 1–5 and 6–10 years. CHMI = controlled human malaria infection; PfCSP = Plasmodium falciparum circumsporozoite protein; PfSPZ = Plasmodium falciparum sporozoites.