Table 2.

Major and minor criteria for the diagnosis of GGS [24]

Major criteria	Minor criteria
Lamellar calcification of the falx < age 20 years	Childhood medulloblastoma
Jaw keratocyst	Lympho-mesenteric or pleural cysts
Palmar/plantar pits (≥ 2)	Macrocephaly (Occipitofrontal Circumference > 97th centile)
Basal cell carcinomas (> 5 in a lifetime or 1 basal cell carcinoma before age of 30)	Cleft lip/palate
First-degree relative with NBCCS	Vertebral/rib anomalies
	Preaxial or postaxial polydactyly
	Ovarian/cardiac fibromas
	Ocular anomalies (e.g., cataract)