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. 2023 Mar 21;29(7):1923–1939. doi: 10.1111/cns.14150

FIGURE 7.

FIGURE 7

Dihydroorotate dehydrogenase regulates the ferroptosis pathway after spinal cord injury. DHODH inhibits the P53/AlOX15 signaling pathway, reduces lipid peroxidation, and ultimately inhibits ferroptosis in rat spinal cord injury models.