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Illustration of PEI-DNA nanoparticle preparation via flash nanocomplexation and the proposed trafficking steps along the GI tract. Reproduced with permission[49]. Citation: Nie T, He Z, Zhou Y, Zhu J, Chen K, Liu L, Leong KW, Mao HQ, Chen Y. Surface Coating Approach to Overcome Mucosal Entrapment of DNA Nanoparticles for Oral Gene Delivery of Glucagon-like Peptide 1. ACS Appl Mater Interfaces 2019; 11: 29593-29603. Copyright© The Authors 2019. Published by American Chemical Society.
