Skip to main content
. Author manuscript; available in PMC: 2023 Jul 6.
Published in final edited form as: IEEE Trans Neural Syst Rehabil Eng. 2023 May 26;31:2424–2437. doi: 10.1109/TNSRE.2023.3276431

Fig. 2.

Fig. 2.

A multi-scale model consisting of (a) bulk tissue model with microelectrode, various retinal layers (GC: ganglion cell; IPL: inner plexiform layer; INL: inner nuclear layer; OPL: outer plexiform layer, ONL: outer nuclear layer and PR: photoreceptor) and (b) morphologically detailed retinal bipolar cell extracted from the connectome inside the AM-NEURON model. The stimulating electrode of 200 μm diameter is placed 60 μm from the axon terminals of BCs. The bulk retinal tissue model is utilized to compute the voltages at every node of the model due to the stimulating microelectrode. These extracellular voltages are then applied to the bipolar cell model to simulate its spatiotemporal response to electrical stimulation.