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. 2021 Jul 1;28(3):150–158. doi: 10.4078/jrd.2021.28.3.150

Figure 2.

Figure 2

Conceptual model on three-step relationship between the exposure, mediator, and outcome. Step 1: association between the wGRS and serologic markers calculated by logistic regression analysis, step 2: association between the wGRS and lupus nephritis (LN) calculated by logistic regression analysis, step 3: association between serologic markers and LN calculated by logistic regression analysis, Sm: Smith, SEA: associated standard error for step 1 calculated by Sobel’s test, SEB: associated SE for step 3 calculated by Sobel’s test, SEA for anti-Sm antibodies: 0.066, SEA for low complement: 0.057, SEB for anti-Sm antibodies: 0.157, SEB for low complement: 0.141.