Table 3.
Relationships among serologic markers, wGRS, and the presence of lupus nephritis
| Variables | OR | CI | p-value | |
|---|---|---|---|---|
| Step 1 | wGRS and Anti-Sm antibodies | 1.27 | 1.11∼1.46 | <0.001 |
| wGRS and low complement | 1.18 | 1.04∼1.32 | 0.008 | |
| Step 2 | wGRS and lupus nephritis | 1.20 | 1.08∼1.34 | 0.001 |
| Step 3 | Anti-Sm antibodies and lupus nephritis | 1.18 | 1.06∼1.31 | 0.004 |
| Low complement and lupus nephritis | 1.19 | 1.06∼1.32 | 0.002 | |
OR: odds ratio, CI: confidence interval, wGRS: weighted genetic risk score, Sm: Smith, Step 1: association between the wGRS and serologic markers, Step 2: association between serologic markers and lupus nephritis, Step 3: association between the wGRS and lupus nephritis. p-values and OR are calculated by logistic regression analyses. p-values<0.05.