Table 1.
Antioxidant effects of lycopene in the broiler's feed.
| Animals | Supplemental dose | Major findings | References |
|---|---|---|---|
| Broiler | 5% lycopene/kg in feed | Decreasing triglycerides, decreasing MDA concentration, and increasing SOD, GPx, ALT, AST, ALP, and lipase concentration | Hosseini-vashan, [8] |
| Broiler | 0 and 75 mg/kg lycopene in feed | Improvement of oxidative stability | Englmaierová et al., [9] |
| Broiler | 0, 200, 400 mg/kg lycopene in feed | Controlling the antioxidant activity of the Nrf2 and NF-kB pathways, muscle keap1, muscle Nrf2, muscle lycopene levels, and the activities of GSH-Px and SOD | Most and yates, [10] |
| Broiler | 50–100 mg/kg lycopene in feed | Decreased the concentration of MDA | Sevcikova et al. [11] |
| Broiler | 200–400 mg/kg | Lowered of cholesterol and MDA and increased activity of HDLC, GPx, and SOD in blood | Fathi et al., [12] |
| Broiler breeder rooster | 0.1–0.3 mM | Improve the quality of rooster spermatozoa after thawing, increase the viability of the hatching eggs | Najafi et al., [13] |
| Broiler exposed aflatoxin B1 | 200 mg/kg | Enhanced GSH, GPx, and SOD activities and decreased H2O2 dan ROS concentration | Wan et al., [14] |
| Broiler exposed aflatoxin B1 | 200 mg/kg | Improved the redox stability by augmenting the antioxidant enzyme activity and their associated mRNA expression levels | Sarker et al., [15] |
| Broiler | 10–30 mg/kg | Raised performance, antioxidant enzyme activities in serum and liver and upregulates genes Keap1-Nrf2 | Wang et al., [16] |
| Broiler | 50–200 mg/kg | Decreased MDA, triglyceride, cholesterol, ALP, ALT and increase catalase, GPx in blood serum | Mezbani et al., [17] |
| Broiler | 10–20 mg/kg | Lowered LDLC, triglyceride and prevents oxidation od LDLC in liver and serum | Lee et al., [18] |
| Arbor acres broiler | 100, 200, 400 mg/kg | Improved growth performance, BW, decrease abdominal fat, plasma lipid level, and hepatic enzymatic activity | Wan et al., [16] |
| Arbor acres broiler (AFB1 challenge) | 100, 200, 400 mg/kg | Decreased ALT, AST, CYP2A6 activities, and hepatic CYP1A1 and increased antioxidant status | Wan et al., [14] |
| Arbor acres broiler (AFB1 challenge) | 100, 200, 400 mg/kg | Increased growth performance, digestive enzyme, and intestinal morphology | Sarker et al., [19] |
| Ross 308 broiler (heat-stress conditions) | 200, 400 mg/kg | Increased growth performance, serum antioxidant status, and muscle antioxidant status | Sahin et al., [20] |
| Hubbard broiler | 500 mg/kg | Decreased growth performance, slaughter performance, | Puzzo et al., [21] |
MDA: malondialdehyde; SOD: superoxide dismutase; GPx: glutathione peroxidase; ALT: alanine aminotransferase; AST: aspartate aminotransferase; ALP: alkaline phosphatase; GSH: reduced glutathione; GSSG: oxidized glutathione; T3: triiodothyronine; HDLC: high density lipoprotein cholesterol; LDLC: low-density lipoprotein cholesterol; NF-kB: nuclear factor kB; Nrf2: nuclear factor erythroid 2-related factor; keap1: Kelch-like-ECH-associated protein 1; H2O2: hydrogen peroxide; ROS: reactive oxygen species.