Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Jul 6;13:10980. doi: 10.1038/s41598-023-38155-0

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

(A) Changes in the mice body weights in each group during the study shown as the percentage change over average initial body weight for each group. Data shown as mean ± SEM and analyzed by ANOVA (n = 10/gp); **p < 0.01; ***p < 0.001 compared to NC group. Lung function parameters analyzed following CDE-exposure and air filtration in each mice group. The (B) airway resistance (R_L) and the (C) dynamic compliance (C_dyn) of anesthetized mice from each group were determined following the increasing dose of methacholine (MCh) (0, 1, 3, 6, 12, 25 and 50 mg/mL) aerosol challenges via inhalation. The histograms showing individual group (D) R_L and (E) C_dyn values for mice challenged with 0, 1, 3, and 6 mg/mL of methacholine. Data shown as mean ± SEM (n = 5/gp) and analyzed by 2-way ANOVA; **p < 0.01.