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. 2023 Jul 6;14:3984. doi: 10.1038/s41467-023-39674-0

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — Vaccine effectiveness estimates after 2 doses of BNT162b2 in the following populations: the original TNCC study sample; all individuals who were sent the questionnaire; non-respondents of the questionnaire; respondents of the questionnaire; respondents using self-reported vaccination status; respondents using self-reported onset dates; respondents excluding those self-reporting as asymptomatic; respondents adjusting for additional confounding (for CEV, household size, and household type); respondents excluding those that delayed their vaccination because they had COVID-19/COVID-19 like symptoms; a combined estimate that accounted for all the above potential biases. All estimates adjusted for confounders that were adjusted for in the original TNCC study (age, gender, ethnicity, geography, index of multiple deprivations, care home status, and week of onset). Points represent odds ratio with corresponding 95% confidence intervals.