Fig. 1. Multi-Omics Binary Integration via Lasso Ensembles (MOBILE) pipeline yields statistically robust, ligand-specific association networks.

The MOBILE data integrator combines multi-omics, multi-assay datasets in a data-driven and central-dogmatic way. By leaving each ligand condition out from the input at a-time, the pipeline outputs robust ligand-specific association networks. These gene-level networks are used to infer differentially enriched pathways and to find regulatory sub-networks.