Table 1.

Differences between the depth and details of prompts for ChatGPT and GPT-4.

Prompts	ChatGPT	GPT-4
Prompt 1 – Diagnosing a patient with ambiguous symptoms	A patient presents with fatigue, weight loss, and occasional dizziness. What are some possible causes for these symptoms?	A 45-year-old male patient presents with a 3-month history of progressive fatigue, unintentional weight loss of 15 pounds, and episodes of dizziness. Please provide a differential diagnosis and suggest relevant diagnostic tests.
Prompt 2 – Treatment recommendations	What are some common treatments for type 2 diabetes?	A 55-year-old female with a recent diagnosis of type 2 diabetes has an HbA1c level of 8.5%. Outline a comprehensive treatment plan, including lifestyle modifications, pharmacological options, and follow-up monitoring.
Prompt 3 – Patient education	Explain high blood pressure in simple terms.	Create a patient-friendly educational handout on hypertension, including an overview of the condition, risk factors, symptoms, potential complications, and management strategies.
Prompt 4 – Reviewing medical research	Tell me about the benefits of exercise for mental health.	Summarize recent research findings on the relationship between physical activity and mental health outcomes, including potential mechanisms, types of exercise, and recommendations for various populations.
Prompt 5 – Clinical case scenario	Describe a patient with pneumonia.	Create a detailed clinical case scenario involving a 65-year-old patient presenting with community-acquired pneumonia, including history of present illness, relevant past medical history, physical examination findings, diagnostic test results, and treatment plan.