Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Jul 7;9:230. doi: 10.1038/s41420-023-01513-y

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 1 — A TLR3 expression is decreased in rhabdomyosarcomas (RMS) compared to their non-tumoral counterpart, i.e. normal skeletal muscles (p-value = 0.0016, unpaired two-sided Wilcoxon test). Publicly available transcriptomic data from Schäfer and Welle’s cohort were downloaded from R² cancer. B TLR3 expression is associated to a better overall survival probability in pediatric Fusion Positive-RMS samples (p-value = 0.041, log-rank test). Publicly available E-TABM-1202 transcriptomic data were downloaded from ArrayExpress. C TLR3 expression is associated with a better metastasis-free survival probability in a cohort of pediatric and AYA osteosarcomas (p-value = 0.0059, log-rank test). Publicly available transcriptomic data from Kuijjer’s cohort were downloaded from R² cancer.