Fig. 3.

A 62-year-old man with clinical suspicion of prostate cancer (PSA total value of 12.9 ng/mL, PSA density of 0.18 ng/mL²). a T2WI acquired on the axial plane showing hypointense nodular lesion on the mid-left posterior peripheral zone, with mild post-contrast enhancement on DCE images (b), with marked restriction diffusion at b-value 2000 (c) and low ADC value (d), classified as PI-RADS 4. e, f The lesions was biopsied using MRI-TRUS TBx. Histopathology confirmed the presence of clinically significant prostate cancer, ISUP 3 (GS 4 + 3). PSA, Prostate-specific antigen; T2WI, T2-weighted imaging; DCE, dynamic contrast-enhanced; TBx, targeted biopsy; ISUP, International Society of Urogenital Pathology; GS, Gleason score