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. 2023 Apr 1;51(8):1769–1780. doi: 10.1007/s10439-023-03183-4

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© The Author(s) 2023

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Average depth-wise orientation profiles of the structure tensor analysis (integration window radius 15, VOI: 150 µm × 5 µm × cartilage thickness, blue lines) and the polarized light microscopy (PLM, red lines) of the lateral and medial femoral condyle cartilage of the healthy (CNTRL) and the experimental (ACLT) rabbit knee joints.