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. 2023 Jul 6;43(7):BSR20222523. doi: 10.1042/BSR20222523

Figure 7. S100A9 is highly expressed in macrophages.

Figure 7

(A and B) S100A9 is predominantly expressed in normal tissues both in mRNA and protein levels. (C) The ssGSEA method quantifies the association of S100A9 expression with the abundance of 24 immune cells in the tumor immune microenvironment. (D) Co-immunofluorescent staining for S100A9 (in green) and the macrophage marker CD68 (in red) showed extensively co-localization in human HCC specimen. Pearson's correlation coefficient was calculated using JACoP tool in ImageJ. Scale bar represents 10 μm. Abbreviations: aDC, activated dendritic cell; CPTAC, Clinical Proteomic Tumor Analysis Consortium; ICGC, International Cancer Genome Consortium; iDC, immature dendritic cell; NK, natural killer cell; pDC, plasmacytoid dendritic cell; Tcm, central memory T cell; Tem, effector memory T cell; Tfh, follicular helper T cell; Tgd, gamma delta T cell; Th1, type I T helper cell; Treg, regulatory T cell.