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. 2023 Jan 11;13(6):2747–2764. doi: 10.1016/j.apsb.2023.01.003

Table 4.

RT inhibitory activity of some selected compounds.

Compd. R10L2 R10L4 R13L2 IAS-0 EFVb
IC50 (μmol/L)a 0.060 ± 0.009 0.070 ± 0.009 0.057 ± 0.012 0.018 ± 0.002 0.030 ± 0.000
a

IC50: Compound concentration required to inhibit 50% incorporation of biotin-labeled UTP by HIV-1 (WT) RT.

b

All data were obtained from one batch with the same method.