Table 1.

Diseases involved in HDACs.

HDACs	Diseases	Ref.
HDAC1	Cancers, cardiovascular diseases, allergic diseases, memory and learning, neurodegenerative disorders, viral infections, osteoarthritis, allergic rhinitis.	12, 13, 14, 15, 16, 17
HDAC2	Cancers, liver diseases, memory and learning, neurodegenerative disorders, viral infections, osteoarthritis, cognitive deficits, diabetes mellitus, airway diseases, chronic obstructive pulmonary disease, cardiac hypertrophy.	13, 14, 15, 16,18, 19, 20, 21, 22, 23
HDAC3	Cancers, obesity, diabetes mellitus, neurodegenerative disorders, rheumatoid arthritis, inflammations, cardiovascular diseases, memory and learning, osteoarthritis, allergic rhinitis, cognitive deficits, lung and kidney diseases.	16,17,20,24,25
HDAC8	Cancers, cornelia de lange syndrome (CdLS), X-linked disorders, infectious diseases, duchenne muscular dystrophy (DMD), cardiovascular diseases, liver fibrosis, pulmonary diseases, hepatic diseases, myopathy, renal fibrosis, neuroinflammation-mediated diseases.	26,27
HDAC4	Cognitive disorders, neurodegenerative disorders.	28,29
HDAC5	Vascular hypertrophy, diabetes mellitus, schizophrenia, neurodegenerative disorders.	20,30
HDAC7	Cancers, osteoarthritis, autoimmune diseases, inflammatory bowel diseases, systemic sclerosis, peyronie's diseases, type 2 diabetes mellitus, hepatic steatosis, liver fibrosis, primary sclerosing cholangitis, respiratory diseases, cystic fibrosis, acute lung injury, huntington's diseases.	31
HDAC9	Cerebrovascular diseases, osteoporosis, autoimmune diseases, cancers, obesity, liver fibrosis.	32
HDAC6	Cancers, neurodegenerative disorders, cardiovascular diseases, inflammatory diseases, autoimmune diseases, viral infections, cognitive deficits.	20,33, 34, 35
HDAC10	Cancers, schizophrenia, HIV infection, intracerebral hemorrhage and immunoglobulin A nephropathy.	36
HDAC11	Allergic rhinitis, neurological and mental disorders, metabolic disorders, cancers, age-related macular degeneration.	17,37,38