Table 1.
Content statistics of ETCM v2.0.
| Data type | Number | Resources |
|---|---|---|
| TCM Formulas | 48,442 | Traditional Chinese Medicine Formulas |
| Chinese Patent Drugs | 9872 | China Food and Drug Administration (http://eng.sfda.gov.cn/WS03/CL0755/) |
| Chinese Patent Drugs with quantitative information of marker ingredients | 865 | Pharmacopoeia of the People's Republic of China (2020 version) |
| Chinese medicinal materials | 2079 | |
| Herbs | 2005 | The Fourth National Survey on Chinese Materia Medica Resources (http://www.zyzypc.com.cn/), Pharmacopoeia of the People's Republic of China (2020 version), Authoritative Chinese Medical Books and Dictionaries |
| Animal medicine | 44 | Pharmacopoeia of the People's Republic of China (2020 version) |
| Mineral medicine | 30 | Pharmacopoeia of the People's Republic of China (2020 version) |
| Chinese medicinal materials with quantitative information of marker ingredients | 504 | Pharmacopoeia of the People's Republic of China (2020 version) |
| Herbs with referenced targets | 990 | Identified by D3CARP platform based on BindingDB database (updated on 2021-11-01) |
| Ingredients | 38,298 | Pharmacopoeia of the People's Republic of China (2020 version) and other literatures |
| Ingredients with referenced targets | 25,647 | Identified by D3CARP platform based on BindingDB database (updated on 2021-11-01) |
| Ingredients with drug-likeness evaluation | 38,265 | A quantitative estimate model of drug-likeness reported by Bickerton group [Nat Chem. 2012 Jan 24; 4 (2):90–8]14 |
| Drug target genes | 1040 | Identified by D3CARP platform based on BindingDB database (updated on 2021-11-01) |
| Targets with references | 1040 | |
| Diseases | 8045 | MalaCards v5.0, Human Phenotype Ontology (HPO, Released in 2018), Online Mendelian Inheritance in Man (OMIM, Released in April 2018), Database of gene-disease associations (DisGeNET v5.0), the portal for rare diseases and orphan drugs (ORPHANET v5.49.0) |
| Diseases with relevant genes | 8038 |