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. 2023 Mar 25;13(6):2680–2700. doi: 10.1016/j.apsb.2023.03.019

Figure 1.

Figure 1

Decreased SIRT6 expression and increased lactate accumulation were observed in the plasma of anthracyclines-treated cancer patients. (A) Ten breast cancer patients received postoperative adjuvant therapy with anthracyclines-based chemotherapy regimens, and plasma was collected before and after chemotherapy from same patients. SIRT6 expression in the plasma of cancer patients was measured by ELISA (n = 10 patients). (B) Lactate concentration in the plasma of cancer patients was measured (n = 10 patients). The data are expressed as the mean ± standard deviation. Two-tailed paired t tests were performed to determine significant differences. ∗∗∗P < 0.001.