Table 2.
HIV-1 reservoir in T cell subsets
|
ID |
Provirus (QVOA day 7) |
poly-A (QVOA day 14) |
GERDA (QVOA day 14) |
QVOA |
||
|---|---|---|---|---|---|---|
| HIV-1 DNA/106 | HIV-1 poly-A/106 | HIV-1 RNA/HIV-1 DNA | HIV-1 Gag+ per 106 | HIV-1 Gag+/Env+ per 106 | IUPM | |
| P01_46_T4_TN | 250 | 85,297 | 341 | 7 | 0.4 | N/D |
| P01_46_T4_TCM | 155,113 | 85,513,919 | 551 | 6,690 | 490 | 4.01 |
| P01_46_T4_TTM | 6,433 | 10,158 | 2 | 70 | 35 | N/D |
| P01_46_T4_TEM | N/D | N/D | N/D | N/D | N/D | N/D |
Representative data of individual P01_46. Proviral quantification was done 7 days after stimulation; poly-A and GERDA quantification were done 14 days after stimulation. Results are normalized to 1 × 106 cells. IUPM, infectious units per million; ND, not detectable; QVOA, quantitative viral outgrowth assay; poly-A, HIV-1 poly-A transcripts.