Table 1.
Patient Characteristics
| Controls | WBRT | |
|---|---|---|
| Variable | Number (%) | Number (%) |
| N | 4148 | 72 |
| Age (years) | ||
| Median | 73 | 62 |
| Range | 42 – 95 | 32 - 85 |
| Sex | ||
| Male | 1929 | 20 (28) |
| Female | 2219 | 52 (72) |
| Karnofsky Performance Status | ||
| 90–100 | n/a | 30 (42) |
| 70–80 | 33 (46) | |
| <70 | 9 (12) | |
| # Brain metastases | ||
| 0 | n/a | 2 (3) |
| 1–4 | 14 (19) | |
| ≥5 | 57 (79) | |
| Organ Site | ||
| Breast | n/a | 32 (44) |
| Lung | 30 (42) | |
| Other | 11 (15) | |
| WBRT dose (Gy) | ||
| Median | n/a | 30 |
| Range | 25 – 37.5 | |
| Median follow up (months) | 12.0 | 6.2 |
| Prior Resection | n/a | |
| Yes | 4 (6) | |
| No | 68 (94) | |
| Prior SRS | n/a | |
| Yes | 17 (18) | |
| No | 55 (82) | |
| Prior systemic therapy | n/a | |
| Yes | 58 (81) | |
| No | 14 (19) | |
| Post-WBRT systemic therapy | n/a | |
| Yes | 72 (100) | |
| No | 0 (0) | |
| Concurrent memantine | n/a | |
| Yes | 16 (29) | |
| No | 40 (71) | |
| Steroid use | n/a | |
| Yes | 24 (43) | |
| No | 32 (57) | |