Table 3.

Estimated aging pace comparison between patients who underwent c-WBRT vs HA-WBRT. $\phi$ > 1 indicated c-WBRT patients “aged” faster compared to HA-WBRT patients and non-significant $\phi$ indicated no difference in ${\mathrm{\Delta }}^{Age}$ between groups. *Bonferroni cutoff p < 0.005 for uncorrected p-values.

Structure	φ (95% CI)	Uncorrected p-value
Whole Brain	−0.674 (−4.36, 3.02)	0.720
Cortex	−3.40 (−6.91, 0.114)	0.058
Subcortical	1.77 (−3.02, 6.56)	0.468
Nucleus Accumbens	0.731 (−3.24, 4.70)	0.718
Amygdala	2.34 (−0.921, 5.59)	0.160
Caudate	−2.15 (−6.12, 1.82)	0.288
Hippocampus	8.83* (3.63, 14.0)	0.001*
Pallidum	−0.353 (−4.34, 3.63)	0.862
Putamen	5.49 (0.721, 10.3)	0.02
Thalamus	6.28 (−0.004, 10.7)	0.042