Figure 6.
Intratumoral XUC treatment and combined therapy display systemic anti-tumor responses in bilateral MBT-2 tumor models. MBT-2 cells (1 × 106 for each side) were inoculated in both sides of mice. The MBT-2 tumor-bearing mice were either untreated or treated with intratumoral XUCs into tumors on one side but not the other side. Tumor growth on the left (injected) and right (not injected) sides was monitored and average tumor volume was determined. Tumor volume follow-up of the injected and distant tumors in the different groups of treatment (A) Vehicle, (B) Intratumoral XUC treatment, (C) GC treatment, (D) Combined therapy with GC and intratumoral XUCs.