Table 2.
Included studies of gastric cancer screening.
| Author year | Study location | Target age, year | Screening modality | Screening invitation | Availability of screening program | Exposure, cycles [year] | Attendance ratea, % | Follow-up period | Analyzed subjects, n |
|---|---|---|---|---|---|---|---|---|---|
| Studies in screen-naïve population with control group | |||||||||
| Quasi-experimental studies | |||||||||
| Rosero-Bixby 200721 | Costa Rica (Cartago) | 50–75 | UGIS | Twice only, biennial | 1996– | ≥1 [1996–2004] | 76 | 1996–2004 | 18,777 |
| Cohort studies | |||||||||
| Chen 200922 | China (Ci-xian) | 40–69 | EGD | Single | 2001–2002 | 1 [2001–2002] | 53 | 2002–2008 | 15,325 |
| Chen 202123 | China (Multi regions) | 40–69 | EGD | Single | 2005–2006 | 1 [2005–2012] | 34 | 2005–2015 | 637,500 |
| Studies in screen-naïve population | |||||||||
| Cohort studies | |||||||||
| Nakamura 197724 | Japan (Fukuoka) | 40– | UGIS | Annual | 1964– | ≥1 [1964–1975] | 29 | 1964–1975 | 1553 |
| Hisamichi 198425 | Japan (Miyagi) | 40–69 | UGIS | Annual | 1960– | ≥1 [1960–1977] | 14 | 1960–1977 | 7008 |
| Kim 201826 | South Korea (four regions) | 40– | UGIS; EGD | Biennial | 2002– | ≥1 [2002–2014] | 31 | 1993–2014 | 15,682d |
| Li 202227 | China (Linqu) | 40–69 | EGD | Single | 2012– | 1 [2012–2018] | 4 | 2012–2019 | 375,800 |
| Studies in regions with population-based screening programs | |||||||||
| Cohort studies | |||||||||
| Inaba 199928 | Japan (Gifu) | 41– | UGIS | Annual | 1960s– | 1 [1991–1992] | 14 | 1992–1995 | 24,134 |
| Mizoue 200329 | Japan (Multi regions) | 40–79 | UGIS | Annual | 1960s– | 1 [1988–1990] | 13 | 1988–1997 | 87,312 |
| Lee 200630 | Japan (Multi regions) | 40–59 | UGIS | Annual | 1960s– | 1 [1990] | 13 | 1990–2003 | 42,150 |
| Miyamoto 200731 | Japan (Miyagi) | 40–64 | UGIS | Annual | 1960– | 1 [2003] | 20 | 1990–2001 | 41,394 |
| Hamashima 201532 | Japan (Tottori) | 40–79 | UGIS; EGD | Annual | 1960s–;b 2000–c | 1 [2007–2008] | 25 | 2007–2013;b 2008–2013c | 14,274 |
| Hagiwara 202133 | Japan (Gunma) | 40–79 | UGIS; EGD | Annual | 1960s–;b 2004–c | 1 [2006] | 21 | 2006–2012 | 21,802 |
| Narii 202234 | Japan (Multi regions) | 50– | UGIS | Annual | 1960s– | 2 [1995–1998; 2000–2003] | 13 | 2000–2015 | 80,272 |
| Case-control studies | |||||||||
| Oshima 198635 | Japan (Osaka) | 40– | UGIS | Annual | 1962– | ≥1 [1962–1981] | 21 | 1969–1981 | 351 |
| Pisani 199436 | Venezuela (Tachira) | 35– | UGIS | Annual to biennial | 1980– | 1981–1989 | 12 | 1985–1989 | 2651 |
| Abe 199537 | Japan (Chiba) | 40– | UGIS | Annual | 1968– | 1968–1989 | 14 | 1981–1989 | 3233 |
| Fukao 199538 | Japan (Miyagi) | 40– | UGIS | Annual | 1960– | 1980–1991 | 22 | 1980–1991 | 775 |
| Hamashima 201339 | Japan (Tottori + Niigata) | 40–79 | UGIS; EGD | Annual | 1960s–;b 2000–and 2003–c,e | 1960s;b 2000–2006 and 2003–2010c,d | 25 | 2003–2006 and 2006–2010d | 2702 |
| Matsumoto 201440 | Japan (Nagasaki) | 40– | EGD | Annual | 1960s–1996 (UGIS);b,f 1996–(EGD)c | 1996–2008 | 22 | 2000–2008 | 143 |
| Chen 201641 | China (Linzhou) | 40–69 | EGD | 1-off | 2005– | 2005–2013 | 51 | 2005–2015 | 2189 |
| Jun 201742 | South Korea (Nationwide) | 40– | UGIS; EGD | Biennial | 2002– | 2002–2009 | 21 | 2004–2012 | 272,090 |
EGD = esophagogastroduodenoscopy; NA = not applicable; ND = no data; UGIS = upper gastrointestinal series.
a
Averaged attendance rates during the study period. Data were extrapolated from other resources when not presented in the study report (see Supplemental Table S4).
b
For radiographic screening.
c
For endoscopic screening.
d
Some overlapping cases are possible.
e
Data are for Tottori and Niigata, respectively.
f
Radiographic screening was no longer available since 1996.