TABLE 3.
Mean area under the ROC curve (AUC) for each method and simulation study, with either n = 2 or n = 4 replicates per condition. Standard deviation is included in the parenthesis next to the corresponding mean.
| Simulation study A | Simulation study B | Simulation study C | Simulation study D | |||||
|---|---|---|---|---|---|---|---|---|
| method | n = 2 | n = 4 | n = 2 | n = 4 | n = 2 | n = 4 | n = 2 | |
| 1 | babel | 0.6 (0.007) | 0.6 (0.006) | 0.576 (0.008) | 0.598 (0.007) | 0.615 (0.077) | 0.651 (0.09) | 0.628 (0.024) |
| 2 | baySeq | 0.88 (0.007) | 0.907 (0.008) | 0.692 (0.008) | 0.746 (0.007) | 0.861 (0.026) | 0.891 (0.031) | 0.751 (0.016) |
| 3 | DESeq2 | 0.8 (0.007) | 0.86 (0.007) | 0.646 (0.01) | 0.748 (0.007) | 0.864 (0.032) | 0.895 (0.035) | 0.718 (0.021) |
| 4 | edgeR | 0.824 (0.018) | 0.865 (0.015) | 0.696 (0.007) | 0.752 (0.007) | 0.878 (0.035) | 0.907 (0.036) | 0.732 (0.035) |
| 5 | riboVI | 0.908 (0.005) | 0.928 (0.004) | 0.827 (0.007) | 0.864 (0.006) | 0.903 (0.014) | 0.939 (0.01) | 0.841 (0.007) |
| 6 | RiboDiff | 0.866 (0.005) | 0.894 (0.005) | 0.691 (0.007) | 0.747 (0.007) | 0.894 (0.019) | 0.935 (0.024) | 0.755 (0.013) |
| 7 | xtail | 0.906 (0.004) | 0.933 (0.004) | 0.713 (0.008) | 0.771 (0.007) | 0.904 (0.034) | 0.941 (0.03) | 0.718 (0.021) |