Table 1. Baseline Patient Characteristics.
Characteristic | No. (%) | |
---|---|---|
Control arm (n = 51) | Experimental arm (n = 45) | |
Age, median (IQR), y | 67 (58-74) | 67 (59-75) |
Sex | ||
Female | 9 (18) | 11 (24) |
Male | 42 (82) | 34 (76) |
Karnofsky Performance Status score | ||
100 | 3 (6) | 4 (9) |
90 | 17 (33) | 20 (44) |
80 | 19 (37) | 17 (38) |
70 | 12 (24) | 4 (9) |
Primary tumor histologic result | ||
Head and neck squamous cell carcinoma | 11 (22) | 9 (20) |
Melanoma | 12 (24) | 11 (24) |
Non–small cell lung carcinoma | 4 (8) | 3 (7) |
Renal cell carcinoma | 8 (16) | 6 (13) |
Urothelial carcinoma | 16 (31) | 16 (36) |
No. of lesions | ||
≤3 | 14 (27) | 10 (22) |
>3 | 37 (73) | 35 (78) |
American Joint Committee on Cancer stage | ||
III | 2 (4) | 6 (13) |
IV | 49 (96) | 39 (87) |
No. of prior systemic treatment lines | ||
0 | 17 (33) | 14 (31) |
1 | 23 (45) | 24 (53) |
≥2 | 11 (22) | 7 (16) |
Prior radiotherapy | 28 (55) | 18 (40) |
Immune checkpoint inhibitor regimen | ||
Atezolizumab every 3 wk | 6 (12) | 5 (11) |
Nivolumab every 2 wk | 21 (41) | 21 (47) |
Nivolumab every 4 wk | 4 (8) | 2 (4) |
Pembrolizumab every 3 wk | 20 (39) | 17 (38) |
No. of SBRT-treated lesions | ||
1 | NA | 16 (36) |
2 | 13 (29) | |
3 | 10 (20) | |
Location of SBRT-treated lesions (n = 69) | ||
Lymph node | NA | 21 (30) |
Lung | 23 (33) | |
Liver | 4 (6) | |
Bone | 9 (13) | |
Other | 12 (17) |
Abbreviations: NA, not applicable; SBRT, stereotactic body radiotherapy.