Table 1:

CNVs detected in KOLF2.1J iPSC lines by high density SNP array.

Sample	Cytoband	Aprox. lengh	Aprox. Coordinates	CNV type	Affected Genes
KOLF2.1J Unedited	3p13	0.1 Mb	Chr3:72,289,657–72,404,542	Deletion	No coding genes
	3q14	0.3 Mb	Chr3:61,242,795–61,528,270	Duplication	No coding genes
	6p22	0.2 Mb	Chr6:15,487,649–15,722,102	Deletion	JARID2 and DTNBP1
	9p22	0.1 Mb	Chr9:119,244,942–119,355,584	Deletion	ASTN2 and ASTN2-AS1
	18q22	0.1 Mb	Chr18:62,115,075–62,264,706	Duplication	No coding genes
KOLF2.1J Edited 1	3p13	0.1 Mb	Chr3:72,289,657–72,404,542	Deletion	No coding genes
	3q14	0.3 Mb	Chr3:61,242,795–61,528,270	Duplication	No coding genes
	6p22	0.2 Mb	Chr6:15,487,649–15,722,102	Deletion	JARID2 and DTNBP1
	9p22	0.1 Mb	Chr9:119,244,942–119,355,584	Deletion	ASTN2 and ASTN2-AS1
	18q22	0.1 Mb	Chr18:62,115,075–62,264,706	Duplication	No coding genes
KOLF2.1J p2	3p13	0.1 Mb	Chr3:72,289,657–72,404,542	Deletion	No coding genes
	3q14	0.3 Mb	Chr3:61,242,795–61,528,270	Duplication	No coding genes
	6p22	0.2 Mb	Chr6:15,487,649–15,722,102	Deletion	JARID2 and DTNBP1
	9p22	0.1 Mb	Chr9:119,244,942–119,355,584	Deletion	ASTN2 and ASTN2-AS1
	18q22	0.1 Mb	Chr18:62,115,075–62,264,706	Duplication	No coding genes
KOLF2.1J p3	3p13	0.1 Mb	Chr3:72,289,657–72,404,542	Deletion	No coding genes
	3q14	0.3 Mb	Chr3:61,242,795–61,528,270	Duplication	No coding genes
	6p22	0.2 Mb	Chr6:15,487,649–15,722,102	Deletion	JARID2 and DTNBP1
	9p22	0.1 Mb	Chr9:119,244,942–119,355,584	Deletion	ASTN2 and ASTN2-AS1
	18q22	0.1 Mb	Chr18:62,115,075–62,264,706	Duplication	No coding genes
KOLF2.1J-NGN2 p10	3p13	0.1 Mb	Chr3:72,289,657–72,404,542	Deletion	No coding genes
	3q14	0.3 Mb	Chr3:61,242,795–61,528,270	Duplication	No coding genes
	6p22	0.2 Mb	Chr6:15,487,649–15,722,102	Deletion	JARID2 and DTNBP1
	9p22	0.1 Mb	Chr9:119,244,942–119,355,584	Deletion	ASTN2 and ASTN2-AS1
	18q22	0.1 Mb	Chr18:62,115,075–62,264,706	Duplication	No coding genes